Nephroangiosclerosis and its pharmacological approach

Curr Vasc Pharmacol. 2011 Mar;9(2):238-43. doi: 10.2174/157016111794519309.

Abstract

Nephroangiosclerosis (NAS) is a major cause of progressive renal insufficiency. Hypertension is very important in the causation of NAS but other factors such as race, age, metabolic variables, and genetics play a pathogenic and prognostic role. A multifactorial treatment strategy, including antihypertensive, lipid-lowering and anti-platelet agents, could improve cardiovascular and renal outcomes in patients with vascular nephropathy.

MeSH terms

  • Animals
  • Antihypertensive Agents / therapeutic use
  • Arteriosclerosis / drug therapy*
  • Arteriosclerosis / etiology
  • Arteriosclerosis / genetics
  • Arteriosclerosis / physiopathology
  • Atherosclerosis / physiopathology
  • Dyslipidemias / physiopathology
  • Humans
  • Hypertension / physiopathology
  • Hypolipidemic Agents / therapeutic use
  • Kidney Diseases / drug therapy*
  • Kidney Diseases / etiology
  • Kidney Diseases / genetics
  • Kidney Diseases / physiopathology
  • Nephrosclerosis / etiology
  • Platelet Aggregation Inhibitors / therapeutic use

Substances

  • Antihypertensive Agents
  • Hypolipidemic Agents
  • Platelet Aggregation Inhibitors