LC-MS-SPE-NMR for the isolation and characterization of neo-clerodane diterpenoids from Teucrium luteum subsp. flavovirens (perpendicular)

Amaya Castro; Sofia Moco; Josep Coll; Jacques Vervoort

doi:10.1021/np9005025

LC-MS-SPE-NMR for the isolation and characterization of neo-clerodane diterpenoids from Teucrium luteum subsp. flavovirens (perpendicular)

J Nat Prod. 2010 May 28;73(5):962-5. doi: 10.1021/np9005025.

Authors

Amaya Castro¹, Sofia Moco, Josep Coll, Jacques Vervoort

Affiliation

¹ Institut de Quimica Avancada de Catalunya, Consejo Superior de Investigaciones Cientificas, Barcelona, Spain.

PMID: 20507180
DOI: 10.1021/np9005025

Abstract

neo-Clerodane diterpenes of plant origin are molecules difficult to monitor due to their nonspecific UV/vis absorption. The present work describes for the first time the application of the LC-MS-SPE-NMR technique for the isolation and characterization of three new neo-clerodane diterpenes, 3beta-hydroxyteucroxylepin and teuluteumin A and teuluteumin B, from Teucrium luteum subsp. flavovirens, harvested from two different locations.

Publication types

Research Support, Non-U.S. Gov't

MeSH terms

Diterpenes / chemistry
Diterpenes / isolation & purification*
Diterpenes, Clerodane / chemistry
Diterpenes, Clerodane / isolation & purification*
Molecular Structure
Morocco
Nuclear Magnetic Resonance, Biomolecular
Spectrophotometry, Ultraviolet
Teucrium / chemistry

Substances

3beta-hydroxyteucroxylepin
Diterpenes
Diterpenes, Clerodane
teuluteumin A
teuluteumin B