Essential-oil profile of Salvia brachyodon Vandas, an endemic Dinaric species transferred from Adriatic Coast to the continental climatic conditions, was determined. Hydrodistilled oils obtained from the plant material collected in three-year field trial were subjected to the detailed GC/MS analysis. Hundred and fifty volatile compounds were identified in four samples. Comparison of the chemical composition of the isolated essential oils showed that population collected one year after transfer preserved sesquiterpene character of its oil (74.3%), while all subsequent samples gave the oils of monoterpene type with 1,8-cineole as the principal constituent (22.2-42.3%). The high degree of variation in the qualitative and quantitative composition of the volatile constituents revealed the strong influence of environmental conditions on the nature of plant chemical composition that has an important role in a plant adaptation.