Systemic postoperative pain management following minimally invasive pectus excavatum repair in children and adolescents: a retrospective comparison of intravenous patient-controlled analgesia and continuous infusion with morphine

Pediatr Surg Int. 2010 Jul;26(7):665-9. doi: 10.1007/s00383-010-2619-0. Epub 2010 May 19.

Abstract

Purpose: Optimal postoperative pain management following minimally invasive surgical repair of pectus excavatum is not established. We compared efficacy and adverse effects in patients treated with patient-controlled analgesia (PCA) with those treated with continuous infusion (CI) with morphine in addition to nonsteroidal anti-inflammatory drugs.

Methods: 33 patient records were examined retrospectively: 21 given PCA and 12 CI with morphine. Main outcome variables were used doses of morphine, pain scores every 3 h and adverse effects.

Results: Median (range) used morphine dose was 0.58 (0.21-1.12) and 0.52 (0.34-0.84) mg/kg on the day 1 and 0.3 (0.02-0.6) and 0.33 (0.09-0.53) mg/kg on the day 2 in PCA and CI groups, respectively (p > 0.05). Pain scores were within moderate and low levels during 42 h after surgery and did not differ between the groups. Median (range) oxygen saturation was 96.5 (93-100) and 97 (94-100) in PCA and CI groups, respectively (p > 0.05). Additional oxygen therapy was required in 14.3% in PCA group and 25% in CI group (p > 0.05). The incidence of pulmonary adverse effects was rare and did not differ between the groups.

Conclusion: Both methods of systemic analgesia in addition to non-opioid analgesics were equally effective and resulted in a low incidence of pulmonary adverse effects.

Publication types

  • Comparative Study

MeSH terms

  • Adolescent
  • Analgesia, Patient-Controlled / methods*
  • Analgesics, Opioid / administration & dosage*
  • Anesthesia, Intravenous*
  • Anti-Inflammatory Agents, Non-Steroidal / therapeutic use
  • Child
  • Female
  • Funnel Chest / surgery*
  • Humans
  • Infusions, Intravenous
  • Male
  • Morphine / administration & dosage*
  • Pain Measurement
  • Pain, Postoperative / drug therapy*
  • Retrospective Studies
  • Young Adult

Substances

  • Analgesics, Opioid
  • Anti-Inflammatory Agents, Non-Steroidal
  • Morphine