Lithium pipecolinate as a facile and efficient ligand for copper-catalyzed hydroxylation of aryl halides in water

Chem Commun (Camb). 2010 Jul 14;46(26):4767-9. doi: 10.1039/c0cc00434k. Epub 2010 May 21.

Abstract

Direct hydroxylation of a wide scope of aryl halides was catalyzed by a combination of CuI and lithium pipecolinate in water with yields up to 92%.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Catalysis
  • Copper / chemistry*
  • Halogens / chemistry*
  • Iodobenzenes / chemistry
  • Ligands*
  • Lithium / chemistry*
  • Lithium Compounds / chemistry*
  • Pipecolic Acids / chemistry*
  • Water / chemistry

Substances

  • Halogens
  • Iodobenzenes
  • Ligands
  • Lithium Compounds
  • Pipecolic Acids
  • Water
  • Copper
  • Lithium
  • iodobenzene