Meningococcal sepsis

Aust Fam Physician. 2010 May;39(5):276-8.

Abstract

Background: Meningococcal disease remains a significant illness with an overall mortality of around 8%. The majority of deaths occur in the first 24 hours, before the commencement of specialist care. Missing a diagnosis of meningococcal disease is a fear among health care practitioners.

Objective: This article presents a guide to identifying the salient features of meningococcal sepsis and initial management strategies in the primary care setting.

Discussion: Initial presentation is often nonspecific and therefore it is important to have a high index of suspicion in children presenting with fever, lethargy, myalgia, vomiting and headache. These children should be monitored and reviewed carefully. If a nonblanching rash develops, immediate treatment, liaison with a paediatric intensive care unit and urgent hospital transfer is required. Initial management involves assessment and regular review of airway, breathing and circulation. Antibiotics (preferably intravenous cephalosporin) should be administered before hospital transfer.

Publication types

  • Review

MeSH terms

  • Adult
  • Anti-Bacterial Agents / therapeutic use
  • Bacteremia / diagnosis*
  • Bacteremia / mortality
  • Bacteremia / therapy*
  • Child
  • Child, Preschool
  • Combined Modality Therapy
  • Critical Illness / therapy
  • Early Diagnosis
  • Emergency Treatment / methods
  • Family Practice / standards
  • Family Practice / trends
  • Female
  • Humans
  • Infant
  • Male
  • Meningitis, Meningococcal / diagnosis
  • Meningitis, Meningococcal / mortality
  • Meningitis, Meningococcal / therapy
  • Meningococcal Infections / diagnosis*
  • Meningococcal Infections / mortality
  • Meningococcal Infections / therapy*
  • Monitoring, Physiologic / methods
  • Practice Guidelines as Topic
  • Prognosis
  • Survival Analysis

Substances

  • Anti-Bacterial Agents