Abstract
Human papillomavirus causes anal condylomata, high-grade anal intraepithelial neoplasia, and anal squamous cell cancer. We found high-grade intraepithelial neoplasia or squamous cell cancer in 75 (47%) of 159 HIV-seropositive men who have sex with men (MSM) and in 42 (26%) of 160 HIV-seronegative MSM with anal condylomata meriting surgery (P<.001, determined by use of the chi(2) test). Anal condylomata in MSM often harbor high-grade intraepithelial neoplasia and squamous cell cancer.
Publication types
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Research Support, Non-U.S. Gov't
MeSH terms
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Adolescent
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Adult
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Aged
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Alphapapillomavirus
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Anus Diseases / complications*
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Anus Diseases / surgery
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Anus Diseases / virology
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Anus Neoplasms / complications
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Anus Neoplasms / epidemiology*
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Anus Neoplasms / pathology
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Carcinoma, Squamous Cell / complications
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Carcinoma, Squamous Cell / epidemiology*
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Carcinoma, Squamous Cell / pathology
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Cohort Studies
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Condylomata Acuminata / complications*
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Condylomata Acuminata / surgery
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Condylomata Acuminata / virology
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HIV Seronegativity
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HIV Seropositivity / complications
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Homosexuality, Male*
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Humans
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Male
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Middle Aged
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Neoplasm Invasiveness
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Papillomavirus Infections / complications*
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Retrospective Studies
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Young Adult