Not all autophagy membranes are created equal

David G McEwan; Ivan Dikic

doi:10.1016/j.cell.2010.04.030

Not all autophagy membranes are created equal

Cell. 2010 May 14;141(4):564-6. doi: 10.1016/j.cell.2010.04.030.

Authors

David G McEwan¹, Ivan Dikic

Affiliation

¹ Frankfurt Institute for Molecular Life Sciences, Goethe University School of Medicine, Theodor-Stern-Kai 7, D-60590 Frankfurt am Main, Germany. mcewan@biochem2.uni-frankfurt.de

PMID: 20478247
DOI: 10.1016/j.cell.2010.04.030

Abstract

During starvation, the cell recycles cytoplasmic material by sequestering it in double-membrane organelles, called autophagosomes, which eventually fuse with lysosomes. In this issue, Hailey et al. (2010) identify the outer membrane of mitochondria as a new source of autophagosomal membranes during starvation.

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