[The use of oral lacosamide in a patient with refractory partial epileptic status]

Rev Neurol. 2010 May 16;50(10):603-6.
[Article in Spanish]

Abstract

Introduction: Generalised epileptic status is a medical emergency with a well-defined therapeutic algorithm. Nevertheless, in the partial status, treatment must be tailored to each patient and the risk of intensive treatment has to be assessed. Unlike generalised epileptic status, partial status is not considered a medical emergency, which means that when it comes to choosing a type of treatment the risk-benefit ratio must be carefully evaluated bearing in mind the characteristics of each particular case.

Case report: A 72-year-old male with partial status secondary to an ischaemic lesion which was refractory to conventional treatment; treatment was established with lacosamide and his condition was rapidly inverted. This is the third case that has been reported of epileptic status being treated with this drug and the second in which it is employed orally.

Conclusions: Although further research is required, lacosamide could be a good therapeutic option with few interactions and side effects.

Publication types

  • Case Reports

MeSH terms

  • Acetamides / therapeutic use*
  • Administration, Oral
  • Aged
  • Electroencephalography
  • Epilepsies, Partial / drug therapy*
  • Humans
  • Lacosamide
  • Magnetic Resonance Imaging
  • Male

Substances

  • Acetamides
  • Lacosamide