Cerebral venous thrombosis in an adolescent with ulcerative colitis

Brain Dev. 2011 Jan;33(1):49-51. doi: 10.1016/j.braindev.2010.04.006. Epub 2010 May 15.

Abstract

We describe a 17-year-old Caucasian adolescent with ulcerative colitis who presented with cerebral venous sinus thrombosis. Laboratory investigation revealed low protein S levels. With successful management the patient remained without neurologic sequalae. Although there may be an association between ulcerative colitis and cerebral venous sinus thrombosis, the exact pathophysiologic mechanism remains unknown.

Publication types

  • Case Reports

MeSH terms

  • Adolescent
  • Anticoagulants / therapeutic use
  • Colitis, Ulcerative / pathology
  • Colitis, Ulcerative / physiopathology*
  • Humans
  • Intracranial Thrombosis / drug therapy
  • Intracranial Thrombosis / pathology*
  • Intracranial Thrombosis / physiopathology
  • Magnetic Resonance Imaging
  • Male
  • Protein S / metabolism
  • Venous Thrombosis / drug therapy
  • Venous Thrombosis / pathology*
  • Venous Thrombosis / physiopathology
  • Warfarin / therapeutic use

Substances

  • Anticoagulants
  • Protein S
  • Warfarin