Abstract
We describe a 17-year-old Caucasian adolescent with ulcerative colitis who presented with cerebral venous sinus thrombosis. Laboratory investigation revealed low protein S levels. With successful management the patient remained without neurologic sequalae. Although there may be an association between ulcerative colitis and cerebral venous sinus thrombosis, the exact pathophysiologic mechanism remains unknown.
Copyright © 2010 Elsevier B.V. All rights reserved.
MeSH terms
-
Adolescent
-
Anticoagulants / therapeutic use
-
Colitis, Ulcerative / pathology
-
Colitis, Ulcerative / physiopathology*
-
Humans
-
Intracranial Thrombosis / drug therapy
-
Intracranial Thrombosis / pathology*
-
Intracranial Thrombosis / physiopathology
-
Magnetic Resonance Imaging
-
Male
-
Protein S / metabolism
-
Venous Thrombosis / drug therapy
-
Venous Thrombosis / pathology*
-
Venous Thrombosis / physiopathology
-
Warfarin / therapeutic use
Substances
-
Anticoagulants
-
Protein S
-
Warfarin