Siderophore-mediated iron acquisition in Bacillus anthracis and related strains

Microbiology (Reading). 2010 Jul;156(Pt 7):1918-1925. doi: 10.1099/mic.0.039404-0. Epub 2010 May 13.

Abstract

Recent observations have shed light on some of the endogenous iron-acquisition mechanisms of members of the Bacillus cereus sensu lato group. In particular, pathogens in the B. cereus group use siderophores with both unique chemical structures and biological roles. This review will focus on recent discoveries in siderophore biosynthesis and biology in this group, which contains numerous human pathogens, most notably the causative agent of anthrax, Bacillus anthracis.

Publication types

  • Review

MeSH terms

  • Animals
  • Anthrax / metabolism
  • Anthrax / microbiology
  • Bacillus anthracis / genetics
  • Bacillus anthracis / metabolism*
  • Biological Transport
  • Humans
  • Iron / metabolism*
  • Siderophores / metabolism*

Substances

  • Siderophores
  • Iron