Objective: To review the role of integrin in nervous system injury and its repair, and to analyze the possible mechanisms.
Methods: Recent literature concerning integrin and its role in nervous system injury was reviewed and analyzed.
Results: Integrin and its related signalling pathway were involved in nervous system injury, especially hypoxic-ischemic nervous injury, and their repair processes.
Conclusion: Intervention of integrin signalling pathway would be a potential strategy to treat nervous system injury, especially hypoxic-ischemic nervous injury.