Controversy of corticosteroids in septic shock

J Nippon Med Sch. 2010 Apr;77(2):67-70. doi: 10.1272/jnms.77.67.

Abstract

The mortality rate of septic shock remains high. The guidelines of the Surviving Sepsis Campaign were published in 2004 and were revised in 2008. Steroid therapy is prominent in the guidelines but remains controversial. In this review, steroid therapy for septic shock is discussed with various landmark papers.

Publication types

  • Historical Article
  • Review

MeSH terms

  • Adrenal Cortex Hormones / adverse effects
  • Adrenal Cortex Hormones / history
  • Adrenal Cortex Hormones / therapeutic use*
  • Evidence-Based Medicine
  • Health Promotion
  • History, 20th Century
  • History, 21st Century
  • Humans
  • Practice Guidelines as Topic
  • Shock, Septic / drug therapy*
  • Shock, Septic / history
  • Shock, Septic / mortality
  • Treatment Outcome

Substances

  • Adrenal Cortex Hormones