[Roles of dendritic cell in disease progression of AIDS primate models]

Hou-Jun Xia; Gao-Hong Zhang; Yong-Tang Zheng

doi:10.3724/sp.j.1141.2010.01057

[Roles of dendritic cell in disease progression of AIDS primate models]

Dongwuxue Yanjiu. 2010 Feb;31(1):57-65. doi: 10.3724/sp.j.1141.2010.01057.

[Article in Chinese]

Authors

Hou-Jun Xia¹, Gao-Hong Zhang, Yong-Tang Zheng

Affiliation

¹ Key Laboratory of Animal Models and Human Disease Mechanisms of the Chinese Academy of Sciences & Yunnan Province, Kunming Institute of Zoology, the Chinese Academy of Sciences, Kunming 650223, China.

PMID: 20446455
DOI: 10.3724/sp.j.1141.2010.01057

Abstract

Non-human primate models are widely used in research of AIDS mechanism, transmission, vaccine and drugs. Dendritic cells (DC), as antigen presenting cells linking the innate immunity and acquired immunity, play a pivotal role in AIDS progression. Studies on the change of DC subsets number, phenotype and function in AIDS non-human primate models are important for revealing some mechanism of AIDS progression. This article reviews the progress in DC subsets of non-human primate AIDS models, which will provide an avenue for further study in AIDS.

Publication types

English Abstract
Research Support, Non-U.S. Gov't
Review

MeSH terms

Acquired Immunodeficiency Syndrome / immunology*
Acquired Immunodeficiency Syndrome / pathology*
Acquired Immunodeficiency Syndrome / virology
Animals
Dendritic Cells / immunology*
Dendritic Cells / virology
Disease Models, Animal*
Disease Progression
Humans
Primates*