Genetic characterization of genogroup I norovirus in outbreaks of gastroenteritis

J Clin Microbiol. 2010 Jul;48(7):2560-2. doi: 10.1128/JCM.00798-10. Epub 2010 May 5.

Abstract

In this study, we demonstrate that differences within the P2 domain of norovirus genogroup I (GI) strains can be used to segregate outbreaks which are unrelated, whereas complete conservation within this region allows tracking of strains that are part of a single outbreak and likely to have a common source.

MeSH terms

  • Caliciviridae Infections* / epidemiology
  • Caliciviridae Infections* / virology
  • Capsid Proteins / genetics
  • Cluster Analysis
  • Disease Outbreaks*
  • Feces / virology
  • Gastroenteritis* / epidemiology
  • Gastroenteritis* / virology
  • Genotype
  • Humans
  • Molecular Sequence Data
  • Norovirus / classification
  • Norovirus / genetics*
  • Phylogeny
  • Polymerase Chain Reaction
  • RNA, Viral / chemistry
  • Sequence Analysis, DNA

Substances

  • Capsid Proteins
  • RNA, Viral

Associated data

  • GENBANK/GQ487570
  • GENBANK/GQ487571
  • GENBANK/GQ487572
  • GENBANK/GQ487573
  • GENBANK/GQ487574
  • GENBANK/GQ487575
  • GENBANK/GQ487576
  • GENBANK/GQ487577
  • GENBANK/GQ487578