Role of MDCT coronary angiography in the evaluation of septal vs interarterial course of anomalous left coronary arteries

J Cardiovasc Comput Tomogr. 2010 Jul-Aug;4(4):246-54. doi: 10.1016/j.jcct.2010.04.002. Epub 2010 Apr 11.

Abstract

Background: Conventional coronary angiography (CCA) may be inaccurate to distinguish between interarterial and septal subtypes of anomalous left coronary arteries (CAs).

Objective: We compared the classification of anomalous left CA arising from the right sinus of Valsalva (RSV) or right CA on the basis of multidetector computed tomography coronary angiography (MDCTCA) with the classification derived from CCA.

Methods: A retrospective review of 6000 consecutive electrocardiographic-gated MDCTCAs identified 15 cases of anomalous left main or left anterior descending CA arising from the RSV or right CA coursing between the aorta and the main pulmonary artery. On the basis of MDCTCA findings, the proximal course of each vessel was classified into 3 subtypes: 1, interarterial; 2, septal; and 3, mixed. CCA was reviewed in 5 cases (33%) and classified according to traditional criteria. When CCA images were not available, 3-dimensional volume-rendered reconstructions were used to simulate CCA.

Results: On the basis of MDCTCA, subtypes were distributed as type 1 (n = 2), type 2 (n = 4), and type 3 (n = 8). One case could not be classified into any of these subtypes and was classified as type 4, right ventricular infundibulum (RVI). Applying CCA criteria, 2 cases would have been classified as interarterial and 14 as septal without appreciation of the mixed or RVI subtypes.

Conclusions: Classification of anomalous left CAs into either septal or interarterial may be too simplistic. There is an anatomic spectrum of anomalous left CAs detected by MDCTCA that challenges the traditional classification based on CCA.

Publication types

  • Comparative Study
  • Multicenter Study
  • Research Support, Non-U.S. Gov't
  • Comment

MeSH terms

  • Adolescent
  • Adult
  • Aged
  • Aortography
  • Coronary Angiography / methods*
  • Coronary Vessel Anomalies / classification
  • Coronary Vessel Anomalies / diagnostic imaging*
  • Female
  • Heart Septum / diagnostic imaging
  • Humans
  • Male
  • Middle Aged
  • Ontario
  • Predictive Value of Tests
  • Pulmonary Artery / diagnostic imaging
  • Radiographic Image Interpretation, Computer-Assisted
  • Retrospective Studies
  • Sinus of Valsalva / abnormalities
  • Sinus of Valsalva / diagnostic imaging
  • Terminology as Topic
  • Tomography, X-Ray Computed*