An improved route to PUGNAc and its galacto-configured congener

J Org Chem. 2010 Jun 4;75(11):3931-4. doi: 10.1021/jo100614b.

Authors

Ethan D Goddard-Borger¹, Keith A Stubbs

Affiliation

¹ Chemistry M313, School of Biomedical, Biomolecular and Chemical Sciences, The University of Western Australia, 35 Stirling Highway, Crawley, WA 6009, Australia.

PMID: 20443616
DOI: 10.1021/jo100614b

Abstract

An efficient, scalable, and reliable synthesis of PUGNAc and its galacto-configured congener is reported.

Publication types

Research Support, Non-U.S. Gov't

MeSH terms

Acetylglucosamine / analogs & derivatives*
Acetylglucosamine / chemical synthesis
Galactose
Glycosylation
Methods
Oximes / chemical synthesis*
Phenylcarbamates / chemical synthesis*

Substances

Oximes
Phenylcarbamates
N-acetylglucosaminono-1,5-lactone O-(phenylcarbamoyl)oxime
Acetylglucosamine
Galactose