Objective: To evaluate the effectiveness of introduction of national guideline to prevent early-onset group B streptococcal (EOGBS) disease, number of screened women and incidence of GBS colonization.
Design: Retrospective cohort study.
Setting: Department of Obstetrics and Gynaecology, Department of Neonatology, University Hospital Ostrava.
Subject and method: We reviewed 8484 consecutive term pregnancies of women who delivered in our hospital, between years 1999-2001 before the introduction of guideline and years 2003-2005 following the guideline.
Results: In group 1999-2001 there were 12/3581 (3.35 per thousand) neonates with EOGBS infection in which 7/3581 (1.96 per thousand) had invasive disease. In group 2003-2005 there were 14/4903 (2.86 per thousand) neonates with EOGBS infection (p=68,33%), in which 6/4903 (1,22 per thousand) had invasive disease (p=39,52%). Number of screened women in years 2003-2005 increased from 40% to 65%, and 69% respectively. There were 577/3019 (19%) of GBS colonized women.
Conclusion: There was 15% decrease of EOGBS disease following the introduction of guideline. Number of screened women increased by 29% in three-year period. GBS colonization in pregnant women is 19%.