Abstract
The leaf and fruit essential oils of Litsea cubeba, extracted by hydrodistillation, were assessed for anticancer activities. A total of 53 and 50 compounds were identified, respectively from the leaf and fruit oils, and their yields were 13.9 +/- 0.09% and 4.0 +/- 0.03%, v/w, of the oven-dried materials, respectively. The main compound in the leaf oil was 1,8-cineol, and in the fruit oil, citral. The fruit oil, but not that of the leaf, exhibited cytotoxic activity against human lung, liver and oral cancer cells.
MeSH terms
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Antineoplastic Agents / analysis*
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Antineoplastic Agents / chemistry
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Antineoplastic Agents / pharmacology
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Cell Line, Tumor
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Cell Survival / drug effects
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Drugs, Chinese Herbal / chemistry*
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Fruit / chemistry
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Gas Chromatography-Mass Spectrometry
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Humans
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Litsea / chemistry*
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Plant Leaves / chemistry
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Plant Oils / analysis*
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Plant Oils / chemistry
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Plant Oils / pharmacology
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Taiwan
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Terpenes / analysis*
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Terpenes / chemistry
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Terpenes / isolation & purification
Substances
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Antineoplastic Agents
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Drugs, Chinese Herbal
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Plant Oils
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Terpenes