Trastuzumab before breast surgery: is concurrent administration with anthracycline-containing chemotherapy necessary?

Ann Oncol. 2010 Jun;21(6):1376-1377. doi: 10.1093/annonc/mdq228. Epub 2010 Apr 29.

Authors

L Del Mastro¹, C Bighin², G Bini², S Giraudi², P Taveggia², A Levaggi², G Canavese³, G Rescinito⁴, P Pronzato²

Affiliations

¹ Department of Medical Oncology. Electronic address: lucia.delmastro@istge.it.
² Department of Medical Oncology.
³ Department of Surgical Oncology.
⁴ Department of Radiology, National Cancer Research Institute, Genoa, Italy.

PMID: 20430904
DOI: 10.1093/annonc/mdq228

No abstract available

Publication types

Evaluation Study
Letter

MeSH terms

Anthracyclines / administration & dosage*
Antibodies, Monoclonal / administration & dosage*
Antibodies, Monoclonal, Humanized
Antineoplastic Combined Chemotherapy Protocols / administration & dosage
Breast Neoplasms / drug therapy*
Breast Neoplasms / metabolism
Breast Neoplasms / surgery*
Carcinoma, Ductal, Breast / drug therapy*
Carcinoma, Ductal, Breast / metabolism
Carcinoma, Ductal, Breast / surgery*
Combined Modality Therapy
Drug Administration Schedule
Female
Humans
Neoadjuvant Therapy / methods
Randomized Controlled Trials as Topic
Receptor, ErbB-2 / metabolism
Trastuzumab

Substances

Anthracyclines
Antibodies, Monoclonal
Antibodies, Monoclonal, Humanized
ERBB2 protein, human
Receptor, ErbB-2
Trastuzumab