Osteoinduction: translating preclinical promise into clinical reality

Carlo Ferretti; Ugo Ripamonti; Eleftherios Tsiridis; Cyrus J Kerawala; Athanasios Mantalaris; Manolis Heliotis

doi:10.1016/j.bjoms.2009.08.043

Osteoinduction: translating preclinical promise into clinical reality

Br J Oral Maxillofac Surg. 2010 Oct;48(7):536-9. doi: 10.1016/j.bjoms.2009.08.043. Epub 2010 Apr 28.

Authors

Carlo Ferretti¹, Ugo Ripamonti, Eleftherios Tsiridis, Cyrus J Kerawala, Athanasios Mantalaris, Manolis Heliotis

Affiliation

¹ Division of Maxillofacial and Oral Surgery, Chris Hani Baragwanath Hospital, University of the Witwatersrand, Johannesburg, South Africa. ferretti@mweb.co.za

PMID: 20430492
DOI: 10.1016/j.bjoms.2009.08.043

Abstract

This review, the second in a series of three editorials, focuses on the problems of translating basic scientific research on induction of bone into reliable clinical applications.

Publication types

Editorial
Review

MeSH terms

Animals
Bone Morphogenetic Proteins / pharmacology
Bone Regeneration* / drug effects
Bone Regeneration* / genetics
Collagen
Humans
Muscle, Skeletal
Recombinant Proteins / pharmacology
Tissue Engineering
Tissue Scaffolds
Transforming Growth Factor beta / pharmacology

Substances

Bone Morphogenetic Proteins
Recombinant Proteins
Transforming Growth Factor beta
Collagen