(6,7-Dimethoxy-4-methylisoquinolinyl)-(4'-methoxyphenyl)-methanone, a new benzylisoquinoline alkaloid from Beilschmiedia brevipes

Pratiwi Pudjiastuti; Mat Ropi Mukhtar; A Hamid A Hadi; Nurdin Saidi; Hiroshi Morita; Marc Litaudon; Khalijah Awang

doi:10.3390/molecules15042339

(6,7-Dimethoxy-4-methylisoquinolinyl)-(4'-methoxyphenyl)-methanone, a new benzylisoquinoline alkaloid from Beilschmiedia brevipes

Molecules. 2010 Mar 31;15(4):2339-46. doi: 10.3390/molecules15042339.

Authors

Pratiwi Pudjiastuti¹, Mat Ropi Mukhtar, A Hamid A Hadi, Nurdin Saidi, Hiroshi Morita, Marc Litaudon, Khalijah Awang

Affiliation

¹ Department of Chemistry, Faculty of Science and Technology, University Airlangga, Surabaya, Indonesia. tiwi2000@hotmail.com

Abstract

The leaves of Beilschmiedia brevipes provided a new benzylisoquinoline alkaloid: (6,7-dimethoxy-4-methylisoquinolinyl)-(4'-methoxyphenyl)-methanone (1) and O,O-dimethylannocherin A (2), a new natural compound which has been synthesized before. Complete 1H- and 13C-NMR data of both compounds were reported. The structures were established through various spectroscopic methods notably 1D- and 2D-NMR, UV, IR and HRESIMS.

Publication types

Research Support, Non-U.S. Gov't

MeSH terms

Benzylisoquinolines / chemistry*
Benzylisoquinolines / isolation & purification
Isoquinolines / chemistry*
Isoquinolines / isolation & purification
Lauraceae / chemistry*
Plant Leaves / chemistry*

Substances

(6,7-dimethoxy-4-methylisoquinolinyl)-(4'-methoxyphenyl)methanone
Benzylisoquinolines
Isoquinolines
O,O-dimethylannocherin A