Histopathologic patterns of testicular biopsies in infertile azoospermic men with varicocele

Fertil Steril. 2010 Nov;94(6):2482-5, 2485.e1-2. doi: 10.1016/j.fertnstert.2010.03.026. Epub 2010 Apr 22.

Abstract

In azoospermic infertile men with varicocele, testicular biopsy revealed histopathologic patterns that varied from disorganized spermatogenesis with low or moderate sperm scores to early (primary spermatocytes stage) or late (spermatid stage) arrested spermatogenesis or germ cell aplasia and Sertoli cells only. Diagnostic testicular biopsy can be helpful for accurate management of azoospermic infertile men with varicoceles before surgical repair.

MeSH terms

  • Adult
  • Azoospermia / blood
  • Azoospermia / complications
  • Azoospermia / pathology*
  • Biopsy
  • Follicle Stimulating Hormone / blood
  • Humans
  • Infertility, Male / blood
  • Infertility, Male / etiology
  • Infertility, Male / pathology
  • Male
  • Organ Size
  • Sertoli Cells / pathology
  • Sperm Motility
  • Spermatogenesis / physiology
  • Spermatozoa / pathology
  • Testis / pathology*
  • Varicocele / blood
  • Varicocele / complications
  • Varicocele / pathology*

Substances

  • Follicle Stimulating Hormone