Abstract
Four new acylated phenylethanoid oligoglycosides, kankanosides J(1) (1), J(2) (2), K(1) (3), and K(2) (4), were isolated from stems of Cistanche tubulosa (Orobanchaceae) together with isocampneoside I (5). Their structures were elucidated on the basis of chemical and physicochemical evidence. Among them, 3-5 were found to inhibit D-galactosamine-induced cytotoxicity in primary cultured mouse hepatocytes.
Publication types
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Research Support, Non-U.S. Gov't
MeSH terms
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Animals
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Cells, Cultured
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Cistanche / chemistry*
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Drugs, Chinese Herbal / chemistry*
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Galactosamine / metabolism
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Glycosides / chemistry*
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Glycosides / isolation & purification
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Glycosides / pharmacology*
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Hepatocytes / drug effects
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Hepatocytes / metabolism
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Mice
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Molecular Structure
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Plant Stems / chemistry*
Substances
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Drugs, Chinese Herbal
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Glycosides
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kankanoside
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Galactosamine