Gram-positive occult bacteremia in patients with pacemaker and mechanical valve prosthesis: a difficult therapeutic challenge

Europace. 2010 Jul;12(7):999-1002. doi: 10.1093/europace/euq117. Epub 2010 Apr 21.

Abstract

Aims: In pacemaker patients with Gram-positive occult bacteremia, it is reasonable to remove the whole stimulation system, but therapeutic decision is sometimes very challenging.

Methods and results: A young patient at 6 years of age underwent dual-chamber pacemaker implantation due to complete atrioventricular block after mitral valve replacement. He felt well until November 2008, when he suffered from febrile illness with blood cultures disclosing methicillin-resistant staphylococcus aureus strain. Repeated antibiotic courses were effective only in obtaining temporary remissions. Consecutive transoesophageal echocardiography examinations were inconclusive. A labelled leucocyte scintigraphy, showing increased captation along leads, was very helpful and critical in guiding our decision to extract leads.

Conclusion: In equivocal cases, or when the hazard of extraction procedure is presumably high, every accessory diagnostic tool (like scintigraphy with labelled leucocytes) is helpful in establishing a definitive diagnosis and in strengthening a somewhat difficult decision.

Publication types

  • Case Reports

MeSH terms

  • Anti-Bacterial Agents / therapeutic use
  • Bacteremia / diagnosis
  • Bacteremia / etiology*
  • Bacteremia / therapy*
  • Child
  • Device Removal
  • Electrodes, Implanted / adverse effects*
  • Electrodes, Implanted / microbiology*
  • Heart Valve Prosthesis / adverse effects*
  • Heart Valve Prosthesis / microbiology*
  • Humans
  • Male
  • Pacemaker, Artificial / adverse effects*
  • Pacemaker, Artificial / microbiology*

Substances

  • Anti-Bacterial Agents