[Selective internal radiotherapy (SIRT) for hepatocellular carcinoma]

Rofo. 2010 Aug;182(8):660-70. doi: 10.1055/s-0029-1245380. Epub 2010 Apr 19.
[Article in German]

Abstract

Microsphere-based radioembolization represents a new generation of therapeutics in interventional oncology. The intrahepatic application of radioactive microspheres via the hepatic artery allows locoregional therapy of diffuse or multifocal liver tumors, for which to date systemic therapy was the only remaining option. The current standard for this selective internal radiotherapy or radioembolization is yttrium-90 glass or resin microspheres. This review discusses the indications, the technique, and the therapeutic results of microsphere-based radioembolization.

Publication types

  • English Abstract
  • Review

MeSH terms

  • Angiography
  • Brachytherapy / methods*
  • Carcinoma, Hepatocellular / blood supply
  • Carcinoma, Hepatocellular / pathology
  • Carcinoma, Hepatocellular / radiotherapy*
  • Embolization, Therapeutic / methods*
  • Film Dosimetry
  • Glass
  • Hepatic Artery
  • Humans
  • Liver Neoplasms / blood supply
  • Liver Neoplasms / pathology
  • Liver Neoplasms / radiotherapy*
  • Microspheres
  • Neoplasm Staging
  • Radiation Injuries / prevention & control
  • Radiation Protection / methods
  • Radiation Tolerance
  • Radiotherapy Dosage
  • Radiotherapy Planning, Computer-Assisted
  • Resins, Synthetic
  • Tomography, Emission-Computed, Single-Photon
  • Yttrium Radioisotopes / administration & dosage*
  • Yttrium Radioisotopes / adverse effects

Substances

  • Resins, Synthetic
  • Yttrium Radioisotopes