Ubiquitin gets CARDed

Eric J Bennett; J Wade Harper

doi:10.1016/j.cell.2010.03.047

Ubiquitin gets CARDed

Cell. 2010 Apr 16;141(2):220-2. doi: 10.1016/j.cell.2010.03.047.

Authors

Eric J Bennett¹, J Wade Harper

Affiliation

¹ Department of Pathology, Harvard Medical School, Boston, MA 02115, USA.

PMID: 20403317
DOI: 10.1016/j.cell.2010.03.047

Abstract

Ubiquitin-dependent processes are critical for propagating antiviral defense signals during viral infection. In this issue, Zeng et al. (2010) describe how viral RNA and unanchored ubiquitin chains conspire to promote activation of RIG-I and the host cell's antiviral transcriptional program.

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Abstract

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