Stabilizing a weak binding state for effectors in the human ras protein by cyclen complexes

Angew Chem Int Ed Engl. 2010 May 17;49(22):3830-3. doi: 10.1002/anie.200907002.
No abstract available

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Binding Sites
  • Coordination Complexes / chemistry*
  • Crystallography, X-Ray
  • Cyclams
  • Drug Design
  • Heterocyclic Compounds / chemistry*
  • Humans
  • Magnetic Resonance Spectroscopy
  • Protein Binding
  • Protein Stability
  • Protein Structure, Tertiary
  • Zinc
  • ras Proteins / chemistry*

Substances

  • Coordination Complexes
  • Cyclams
  • Heterocyclic Compounds
  • cyclen
  • ras Proteins
  • Zinc