Phenanthrene derivatives from the stems and leaves of Dioscorea nipponica Makino

J Asian Nat Prod Res. 2010 Jan;12(1):1-6. doi: 10.1080/10286020903403626.

Abstract

From the CHCl(3)-soluble portion of the 70% EtOH extract of the stems and leaves of Dioscorea nipponica Makino, two new phenanthrenes, 7-hydroxy-2,3,5-trimethoxy-9,10-dihydrophenanthrene (1) and 2,2',7,7'-tetrahydroxy-4,4',6,6'-tetramethoxy-1,1'-biphenanthrenes (2), as well as three known phenanthrenes, 6-methoxycoelonin (3), 4,7-dihydroxy-2,3,6-trimethoxyphenanthrene (4), and 3,7-dihydroxy-2,4,6-trimethoxyphenanthrene (5), were isolated. The structures were determined by means of HR-MS, (1)H NMR, (13)C NMR, and HMBC experiments.

MeSH terms

  • Dioscorea / chemistry*
  • Drugs, Chinese Herbal / chemistry
  • Drugs, Chinese Herbal / isolation & purification*
  • Molecular Structure
  • Nuclear Magnetic Resonance, Biomolecular
  • Phenanthrenes / chemistry
  • Phenanthrenes / isolation & purification*
  • Plant Leaves / chemistry
  • Plant Stems / chemistry

Substances

  • 2,2',7,7'-tetrahydroxy-4,4',6,6'-tetramethoxy-1,1'-biphenanthrene
  • 7-hydroxy-2,3,5-trimethoxy-9,10-dihydrophenanthrene
  • Drugs, Chinese Herbal
  • Phenanthrenes