A new fixation strategy for addressable nano-network building blocks

Chem Commun (Camb). 2010 Jun 7;46(21):3714-6. doi: 10.1039/c001513j. Epub 2010 Apr 13.

Abstract

Rapid controlled self-assembly makes DNA ideal for building nanostructures. A problem using hybridized intermediates in hierarchic assembly is their thermodynamic lability. We demonstrate a click-fixation technology by which robust hexagonal DNA modules can be made. This principle is applicable to a wide variety of DNA nanoconstructs.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • DNA / chemistry*
  • Electrophoresis, Polyacrylamide Gel
  • Fluorescence Resonance Energy Transfer
  • Nanostructures / chemistry*
  • Nucleic Acid Hybridization
  • Oligonucleotides / chemistry

Substances

  • Oligonucleotides
  • DNA