Discovery of novel zebrafish neural tracers by organism-based screening of a rosamine library

Chem Commun (Camb). 2010 May 7;46(17):2932-4. doi: 10.1039/b920432f. Epub 2010 Mar 23.

Abstract

Through organism based screening of a rosamine library using zebrafish larvae, novel neural tracers for live imaging were discovered with superior performance.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Animals
  • Drug Discovery
  • Fluorescent Dyes / chemistry*
  • Microscopy, Fluorescence
  • Neurons / metabolism*
  • Organic Chemicals / chemistry
  • Zebrafish / anatomy & histology

Substances

  • Fluorescent Dyes
  • Organic Chemicals
  • red dye CMXRos