Should a "Risk Syndrome for Psychosis" be included in the DSMV?

Schizophr Res. 2010 Jul;120(1-3):7-15. doi: 10.1016/j.schres.2010.03.017. Epub 2010 Apr 10.

Abstract

The proposed Risk Syndrome for Psychosis (RS) criteria are derived from the Ultra High Risk criteria (UHR) and prodromal or Clinical High Risk criteria (CHR), and consist of subthreshold or attenuated positive psychotic symptoms with operationalized recency and frequency criteria. The rationale behind the proposed inclusion of the RS in the Diagnostic and Statistical Manual of Mental Disorders, Fifth Edition (DSMV) is that several studies have found that the UHR/prodromal/CHR criteria predict onset of psychotic disorder, mainly schizophrenia, within a brief time period of a few years. Identifying individuals meeting these criteria thus affords the possibility of early intervention to prevent or delay onset of full blown psychotic disorder. However, the RS is yet to be properly validated. Additionally, there are potential dangerous unintended consequences of the reification of this syndrome as a formal diagnosis. Thus we feel it is premature to justify inclusion of the RS in the DSM.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Diagnostic and Statistical Manual of Mental Disorders*
  • Early Diagnosis
  • Humans
  • Predictive Value of Tests
  • Psychiatric Status Rating Scales
  • Psychotic Disorders / diagnosis*
  • Reproducibility of Results
  • Risk Factors