Abstract
Purpose:
To describe an atypical case of primary intraocular lymphoma (PIOL) with rapid progression leading to vision loss and death.
Methods:
A 71-year-old woman with a history of PIOL presented with a sudden decline in vision. MRI, CSF cytology, and ocular examination 2 months prior were unremarkable.
Results:
Repeat MRI of the brain and orbits at this time revealed a 0.8 x 2.4-cm lesion of the left choroid plexus. LP revealed rare atypical B cells. The patient rapidly deteriorated and died a month later.
Conclusion:
Recognition of the potential for rapid progression and mortality in patients with PIOL is essential.
Publication types
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Case Reports
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Research Support, N.I.H., Intramural
MeSH terms
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Aged
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Antineoplastic Combined Chemotherapy Protocols / administration & dosage
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Blindness / diagnosis*
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Blindness / drug therapy
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Blindness / etiology
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Disease Progression
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Eye Neoplasms / complications*
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Eye Neoplasms / diagnosis
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Eye Neoplasms / drug therapy
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Fatal Outcome
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Female
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Humans
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Lymphoma, B-Cell / complications*
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Lymphoma, B-Cell / diagnosis
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Lymphoma, B-Cell / drug therapy
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Magnetic Resonance Imaging
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Methotrexate / administration & dosage
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Procarbazine / administration & dosage
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Vincristine / administration & dosage
Substances
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Procarbazine
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Vincristine
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Methotrexate