The yin and yang of chromatin spatial organization

Genome Biol. 2010;11(3):204. doi: 10.1186/gb-2010-11-3-204. Epub 2010 Mar 29.

Abstract

Spatial organization of the genome is non-random. Preferential chromatin interactions, both in cis and in trans and between transcriptionally active and silent regions, influence organization.

Publication types

  • Research Support, Non-U.S. Gov't
  • Review

MeSH terms

  • Chromatin / genetics*
  • Chromatin / metabolism*
  • Chromatin Assembly and Disassembly*
  • Gene Expression Regulation / genetics*
  • Genome / genetics*
  • Nucleic Acid Conformation
  • Transcription Factors / metabolism
  • Transcription, Genetic*

Substances

  • Chromatin
  • Transcription Factors