REVIEW: Apathy diagnosis, assessment, and treatment in Alzheimer's disease

CNS Neurosci Ther. 2010 Oct;16(5):263-71. doi: 10.1111/j.1755-5949.2009.00132.x.

Abstract

Apathy is defined as a disorder of motivation. There is wide acknowledgement that apathy is an important behavioral syndrome in Alzheimer's disease and in various neuropsychiatric disorders. In light of recent research and the renewed interest in the correlates and impacts of apathy and in its treatments, it is important to develop criteria for apathy that will be widely accepted, have clear operational steps, and be easy to apply in clinical practice and in research settings. Meeting these needs was the focus for a task force that included members of the European Psychiatric Association, the European Alzheimer's Disease Consortium and experts from Europe, Australia and North America.

Publication types

  • Research Support, Non-U.S. Gov't
  • Review

MeSH terms

  • Alzheimer Disease / complications*
  • Alzheimer Disease / diagnosis
  • Alzheimer Disease / therapy
  • Antipsychotic Agents / pharmacology
  • Antipsychotic Agents / therapeutic use*
  • Apathy / physiology*
  • Humans
  • Mood Disorders* / diagnosis
  • Mood Disorders* / drug therapy
  • Mood Disorders* / etiology
  • Motivation / drug effects
  • Motivation / physiology

Substances

  • Antipsychotic Agents