Characterization of language and phonological working memory in patients with myoclonic astatic epileptic syndrome

Arq Neuropsiquiatr. 2010 Feb;68(1):30-4. doi: 10.1590/s0004-282x2010000100007.

Abstract

The course of myoclonic astatic epileptic syndrome (MAES) is variable and little information is available about cortical functions in the presence of the disease. The objective of the present study was to assess the phonological working memory (PWM) and the verbal language of six patients between 8 and 18 years old, on treatment for at least 5 years, and good control of seizures, diagnosed in the Service of Epilepsy of Hospital of Clinics of Ribeirão Preto, São Paulo University in Brazil. The Test of Repetition of Meaningless Words was used to assess PWM. Video-recorded of language samples were collected during spontaneous and directed activities for the study of verbal language and pragmatics. A qualitative analysis showed that all patients presented deficits in the execution of the PWM test and only one patient showed poor mastery of all aspects studied. These finds contribute to strategies of treatment for language problems of patients with MAES, focusing on PWA.

MeSH terms

  • Adolescent
  • Child
  • Epilepsies, Myoclonic / complications*
  • Epilepsies, Myoclonic / drug therapy
  • Epilepsies, Myoclonic / physiopathology
  • Humans
  • Language Disorders / diagnosis
  • Language Disorders / etiology*
  • Language Disorders / physiopathology
  • Language Tests
  • Memory, Short-Term / physiology*
  • Retention, Psychology / physiology*
  • Verbal Behavior / physiology*