In vivo evaluation of novel pH-sensitive mPEG-Hz-Chol conjugate in liposomes: pharmacokinetics, tissue distribution, efficacy assessment

Artif Cells Blood Substit Immobil Biotechnol. 2010 May;38(3):136-42. doi: 10.3109/10731191003685481.
No abstract available

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Animals
  • Cholesterol / chemistry
  • Drug Delivery Systems / methods
  • Hydrazones / chemistry
  • Hydrogen-Ion Concentration
  • Liposomes / chemistry*
  • Liposomes / pharmacokinetics*
  • Liver Neoplasms, Experimental / drug therapy
  • Mice
  • Mice, Inbred BALB C
  • Paclitaxel / administration & dosage
  • Paclitaxel / chemistry
  • Particle Size
  • Polyethylene Glycols / chemistry*
  • Polyethylene Glycols / pharmacokinetics*
  • Rats
  • Rats, Sprague-Dawley
  • Tissue Distribution

Substances

  • Hydrazones
  • Liposomes
  • Polyethylene Glycols
  • monomethoxypolyethylene glycol
  • Cholesterol
  • Paclitaxel