Risk factors for physical disability at diagnosis of 19,283 new cases of leprosy

Rev Soc Bras Med Trop. 2010 Jan-Feb;43(1):19-22. doi: 10.1590/s0037-86822010000100005.

Abstract

Introduction: The purpose of this study was to evaluate risk factors for physical disability at the moment of leprosy diagnosis.

Methods: This is a retrospective, descriptive and exploratory investigation of 19,283 patients with leprosy, registered in the State of Minas Gerais, Brazil, between 2000 and 2005.

Results: The risk of Grade 2 disability was 16.5-fold higher in patients with lepromatous leprosy, and 12.8-fold higher in patients presenting the borderline form, compared to patients presenting indeterminate leprosy. The occurrence of more than one thickened nerve increased the odds of a patient developing Grade 2 disability, 8.4-fold. Age <15 years, multibacillary leprosy and no formal education presented 7.0, 5.7 and 5.6 odds of developing physical disability, respectively.

Conclusions: These factors should be considered as strong prognostic indicators in the development of physical disability at diagnosis.

Publication types

  • Comparative Study

MeSH terms

  • Adolescent
  • Disability Evaluation*
  • Educational Status
  • Female
  • Humans
  • Leprosy / classification
  • Leprosy / complications*
  • Leprosy / diagnosis
  • Male
  • Peripheral Nervous System Diseases / etiology*
  • Prognosis
  • Retrospective Studies
  • Risk Factors
  • Severity of Illness Index