Long-term outcomes of transvestibular vaginoplasty with pelvic peritoneum in 182 patients with Rokitansky's syndrome

Fertil Steril. 2010 Nov;94(6):2281-5. doi: 10.1016/j.fertnstert.2010.02.010. Epub 2010 Mar 19.

Abstract

Objective: To evaluate the technical feasibility and anatomical and functional outcomes of one-stage transvestibular vaginoplasty with pelvic peritoneum for the patients with Mayer-Rokitansky-Kuster-Hauser (MRKH) syndrome.

Design: A retrospective review of prospectively collected data.

Setting: A university hospital.

Patient(s): A total of 182 women with MRKH syndrome.

Intervention(s): Undergoing transvestibular vaginoplasty with pelvic peritoneum.

Main outcome measure(s): The perioperative results, complications, and anatomical and functional outcomes of transvestibular vaginoplasty with pelvic peritoneum.

Result(s): The mean operative time was 72.2 minutes (range 55-150 minutes). Average blood loss was 78.5 mL (range 40-170 mL). The only perioperative complication was one case of rectal-vaginal fistula. Thirty-four patients had vault granulation at the neovagina, which healed after trimming and the mean length of the neovagina was 9 cm (range 7-12 cm) without any shrinkage at the follow-up of 3 months after operation. The neovaginal introitus admitted two fingers in width in all patients. Good functional outcomes were found in the patients at follow-up 15 years after surgery with 80% of the cumulative proportion of sexual satisfactory activity.

Conclusion(s): Transvestibular vaginoplasty with pelvic peritoneum is an effective and feasible approach for women with MRKH syndrome. The procedure has satisfactory long-term anatomical and functional results.

Publication types

  • Evaluation Study

MeSH terms

  • 46, XX Disorders of Sex Development / rehabilitation
  • 46, XX Disorders of Sex Development / surgery
  • Abnormalities, Multiple / rehabilitation
  • Abnormalities, Multiple / surgery
  • Adult
  • Congenital Abnormalities
  • Feasibility Studies
  • Female
  • Follow-Up Studies
  • Gynecologic Surgical Procedures / methods*
  • Gynecologic Surgical Procedures / rehabilitation*
  • Humans
  • Kidney / abnormalities
  • Models, Biological
  • Mullerian Ducts / abnormalities
  • Pelvis / surgery
  • Peritoneum / surgery*
  • Plastic Surgery Procedures / methods
  • Plastic Surgery Procedures / rehabilitation
  • Postoperative Care
  • Retrospective Studies
  • Somites / abnormalities
  • Spine / abnormalities
  • Time Factors
  • Treatment Outcome
  • Uterus / abnormalities
  • Uterus / surgery
  • Vagina / abnormalities
  • Vagina / physiology
  • Vagina / surgery*
  • Young Adult

Supplementary concepts

  • Mullerian aplasia