Minimal anti-tobacco intervention (MIA) is an efficient and inexpensive method of smoking cessation intervention. The ability for practical use of MIA could be acquired by a majority of physicians-practitioners in Poland and other European Union countries. The objective of the work was to establish a practical knowledge in the scope of anti-tobacco strategies of senior students of the Medical Faculty of the Medical University of Bialystok after six-year education. We also assessed the prevalence of tobacco smoking among students of Medical Faculty. The percentage of tobacco smokers between the last course students of Medical Faculty average at 15% of women and 29% of men. Only 3 of all woman and half of men think they could effectively help in smoking cessation, but most of the assessed students have not acquired sufficient knowledge for an anti-tobacco intervention as well as they don't know practical tools like Fagerstöm Test for Nicotine Dependence or Schneider's Smoker Complaint Scale.