Galectins typically bind β-galactose-containing glycoconjugates and share primary structural homology in their carbohydrate-recognition domains (CRDs). Previously termed S-type lectins, galectins represent a group of proteins that are the most widely expressed class of lectins in all organisms. This chapter describes the diversity of the galectin family and presents an overview of what is known about their biosynthesis, secretion, and biological activities.
Copyright © 2009, The Consortium of Glycobiology Editors, La Jolla, California.