Glycans are components of many biotherapeutic agents, ranging from natural products to molecules based on rational design to recombinant glycoproteins. The glycan components of these agents can be important determinants of their biological activity and therapeutic efficacy. This chapter provides a brief overview of some of the issues pertinent to glycan functions in therapeutics and a few examples of successful glycan or glycoconjugate-based drugs (Table 51.1).
Copyright © 2009, The Consortium of Glycobiology Editors, La Jolla, California.