Photodynamic therapy in periodontal therapy: microbiological observations from a private practice

Gen Dent. 2010 Mar-Apr;58(2):e68-73.

Abstract

In recent years, the combination of laser light and photosensitizer known as photodynamic therapy (PDT) has been used in periodontal therapy. However, there are not enough clinical studies to fully evaluate the effects of PDT on the periodontal tissues. This microbiological study examined the effects of PDT on the periodontal bacteria in combination with scaling and root planing (SRP) in the same group of patients by randomly selecting PDT or SRP for use in different quadrants of the mouth. For the present study, PDT was compared with a diode laser (980 nm) and an Nd:YA G laser (1,064 nm). Microbiological samples were examined and evaluated over a period of three months. Significant bacterial reduction has been observed in all cases. The diode laser with SRP presented long-term positive results, while PDT showed a significant bacteria reduction during the entire observation period.

Publication types

  • Comparative Study
  • Randomized Controlled Trial

MeSH terms

  • Aggregatibacter actinomycetemcomitans / drug effects
  • Aggregatibacter actinomycetemcomitans / radiation effects
  • Bacterial Load
  • Bacteroides / drug effects
  • Bacteroides / radiation effects
  • Dental Scaling / methods
  • Fusobacterium nucleatum / drug effects
  • Fusobacterium nucleatum / radiation effects
  • Gram-Negative Bacteria / drug effects*
  • Gram-Negative Bacteria / radiation effects
  • Humans
  • Lasers, Semiconductor / therapeutic use
  • Lasers, Solid-State / therapeutic use
  • Low-Level Light Therapy / methods
  • Peptostreptococcus / drug effects
  • Peptostreptococcus / radiation effects
  • Periodontal Diseases / drug therapy*
  • Periodontal Diseases / microbiology
  • Photochemotherapy / methods*
  • Photosensitizing Agents / therapeutic use
  • Porphyromonas gingivalis / drug effects
  • Porphyromonas gingivalis / radiation effects
  • Prevotella intermedia / drug effects
  • Prevotella intermedia / radiation effects
  • Root Planing / methods
  • Treponema denticola / drug effects
  • Treponema denticola / radiation effects

Substances

  • Photosensitizing Agents