[Detection of metal elements of skin in electric injury by inductively coupled plasma mass spectrometry]

Fa Yi Xue Za Zhi. 2010 Feb;26(1):6-9.
[Article in Chinese]

Abstract

Objective: To explore the feasibility of the detection of metal elements of skin in electric injury using inductively coupled plasma mass spectrometry (ICP-MS), and to establish a method to detect metal elements of skin in electric injury.

Methods: Brass, copper, aluminum and iron were used as electrodes to make electrical marks on rabbit hindlimb (220V AC), and then ICP-MS was used to detect the metal elements in injured skin.

Results: Comparing with control group,the levels of Cr, Ni, Cu, Zn and Pb showed higher in the group of brass shock (P < 0.05); the levels of Cr, Cu and Pb were higher in group of the copper shock (P < 0.05); the levels of Al, Cr, Mn, Co, Ni, Cu and Pb displayed stronger in group of aluminum shock (P < 0.05); the levels of Cr, Mn, Fe and Ni showed higher in the group of iron shock (P < 0.05). The types and levels of metal elements showed the significant difference between different electrode groups after electric injury.

Conclusion: ICP-MS can be used as an effective tool to determine electric injury, and the method can be used to estimate the features of electrodes.

Publication types

  • English Abstract
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Animals
  • Area Under Curve
  • Copper / analysis
  • Copper / chemistry
  • Electric Injuries*
  • Female
  • Male
  • Mass Spectrometry / methods*
  • Metals / analysis*
  • Metals / chemistry
  • Nickel / analysis
  • Nickel / chemistry
  • Rabbits
  • Random Allocation
  • Skin / chemistry*
  • Skin / injuries*
  • Zinc / analysis
  • Zinc / chemistry

Substances

  • Metals
  • Copper
  • Nickel
  • Zinc