Aminocarnitine ureidic derivatives as inhibitors of carnitine palmitoyltransferase I

ChemMedChem. 2010 May 3;5(5):666-9. doi: 10.1002/cmdc.200900535.
No abstract available

MeSH terms

  • Animals
  • Betaine / analogs & derivatives*
  • Betaine / chemical synthesis
  • Betaine / chemistry
  • Betaine / therapeutic use
  • Binding Sites
  • Carnitine / chemical synthesis
  • Carnitine / chemistry*
  • Carnitine / therapeutic use
  • Carnitine O-Palmitoyltransferase / antagonists & inhibitors*
  • Carnitine O-Palmitoyltransferase / metabolism
  • Computer Simulation
  • Diabetes Mellitus, Type 2 / drug therapy
  • Enzyme Inhibitors / chemical synthesis
  • Enzyme Inhibitors / chemistry*
  • Enzyme Inhibitors / therapeutic use
  • Hypoglycemic Agents / chemical synthesis
  • Hypoglycemic Agents / chemistry*
  • Hypoglycemic Agents / therapeutic use
  • Mice
  • Rats

Substances

  • Enzyme Inhibitors
  • Hypoglycemic Agents
  • Betaine
  • emeriamine
  • Carnitine O-Palmitoyltransferase
  • Carnitine