Peritoneal tuberculosis. Report of seven cases

Cir Cir. 2010 Jan-Feb;78(1):67-71.
[Article in English, Spanish]

Abstract

Background: Peritoneal tuberculosis (TB) is a misdiagnosed clinical entity of low frequency. Due to its rarity, it requires a high index of suspicion in clinical practice. Its incidence has been increasing in recent years.

Clinical cases: We present and analyze seven cases of peritoneal TB diagnosed and treated at four hospitals in Aguascalientes, Mexico during a 5-year period. Mean age of the patients was 47.5 +/- 6.5 years. There were six females and one male. Two patients had a history of treated lung TB. The most frequent clinical data were abdominal pain (six patients), ascites (four patients), and abdominal tumor (three patients). Symptom duration prior to surgery was 5.0 +/- 1.7 months. Abdominopelvic CT examinations revealed unilateral ovarian tumor in four patients, bilateral ovarian tumor in two patients, ascites in four patients, and retroperitoneal adenopathy in one patient. All female patients had elevated serum CA-125 levels with a median of 419 U/ml (range: 286-512 U/ml). All patients had a preoperative diagnosis of malignant tumor. All surgical procedures were elective and consisted of laparotomy with biopsy in three patients, laparotomy with salpingo-oophorectomy in two patients, and laparoscopy with biopsy in two patients. Diagnosis of TB was suspected in all cases during surgery. Mean hospital stay was 2 +/- 0.5 days. There was no postoperative morbidity or mortality.

Conclusions: Peritoneal TB is uncommon. Diagnoses should be considered in all patients with ascites, adnexal tumors and elevated serum CA-125 levels.

Publication types

  • Multicenter Study

MeSH terms

  • Abdominal Pain / etiology
  • Adult
  • Antitubercular Agents / therapeutic use
  • Ascites / etiology
  • Biomarkers
  • CA-125 Antigen / blood
  • Combined Modality Therapy
  • Diagnostic Errors*
  • Elective Surgical Procedures
  • Female
  • Humans
  • Immunocompromised Host
  • Laparotomy
  • Lymphoma / diagnosis
  • Male
  • Mexico / epidemiology
  • Middle Aged
  • Ovarian Neoplasms / diagnosis
  • Ovariectomy
  • Peritoneal Neoplasms / diagnosis
  • Peritoneal Neoplasms / secondary
  • Peritonitis, Tuberculous / complications
  • Peritonitis, Tuberculous / diagnosis
  • Peritonitis, Tuberculous / drug therapy
  • Peritonitis, Tuberculous / epidemiology*
  • Peritonitis, Tuberculous / surgery
  • Young Adult

Substances

  • Antitubercular Agents
  • Biomarkers
  • CA-125 Antigen