Fast whole-brain 4D contrast-enhanced MR angiography with velocity encoding using undersampled radial acquisition and highly constrained projection reconstruction: image-quality assessment in volunteer subjects

AJNR Am J Neuroradiol. 2011 Mar;32(3):E47-50. doi: 10.3174/ajnr.A2048. Epub 2010 Mar 11.

Abstract

We report on the image quality obtained by using fast contrast-enhanced whole-brain 4D radial MRA with 0.75-second temporal resolution, isotropic submillimeter spatial resolution, and velocity encoding (HYPRFlow). Images generated by HYPR-LR by using the velocity-encoded data as the constraining image were of diagnostic quality. In addition, we demonstrate that measurements of shear stress within the middle cerebral artery can be derived from the high-resolution 3D velocity data.

Publication types

  • Research Support, N.I.H., Extramural

MeSH terms

  • Adult
  • Algorithms*
  • Brain / blood supply*
  • Cerebral Angiography / methods
  • Cerebral Arteries / anatomy & histology*
  • Female
  • Humans
  • Image Enhancement / methods
  • Image Interpretation, Computer-Assisted / methods*
  • Magnetic Resonance Angiography / methods*
  • Male
  • Reproducibility of Results
  • Sample Size
  • Sensitivity and Specificity
  • Young Adult