A prussian blue (PB) electrodeposited on nano Ag-coated multiwalled carbon nanotubes (nano Ag-MWNTs) was reported. Also a PB/nano Ag-MWNTs composite modified glass carbon (GC) electrode was used to investigate the electrochemical behavior concerning the reduction of hydrogen peroxide. The experiment results showed that the PB/nano Ag-MWNTs/GC electrode had a wide linear range, a fast response time and high sensitivity toward the electrocatalytic reduction of hydrogen peroxide. PB and nano Ag-MWNTs had a synergistic electrocatalytic effect toward the reduction of hydrogen peroxide. The PB/nano Ag-MWNTs/GC electrode exhibited a wide linear response range of 8 x 10(-8) to 5 x 10(-3) mol/L with a correlation coefficient of 0.998 for the detection of hydrogen peroxide. Also the response time, detection limit (S/N = 3) and sensitivity of the PB/nano Ag-MWNTs/GC electrode were respectively determined to be 2 s, 4 x 10(-8) mol/L and 920 A/mol cm(2). Another attractive characteristic was that the PB/nano Ag-MWNTs/GC electrode showed high stability and reproducibility.