Previews. Crossing boundaries: direct programming of fibroblasts into neurons

Simon M G Braun; Sebastian Jessberger

doi:10.1016/j.stem.2010.02.004

Previews. Crossing boundaries: direct programming of fibroblasts into neurons

Cell Stem Cell. 2010 Mar 5;6(3):189-91. doi: 10.1016/j.stem.2010.02.004.

Authors

Simon M G Braun¹, Sebastian Jessberger

Affiliation

¹ Institute of Cell Biology, Department of Biology, Swiss Federal Institute of Technology (ETH) Zurich, Schafmattstrasse 18, 8093 Zurich, Switzerland.

PMID: 20207219
DOI: 10.1016/j.stem.2010.02.004

Abstract

In a recent paper in Nature, Vierbuchen et al. (2010) show that fibroblasts can be directly converted into functional neurons by defined factors. This finding sheds new light on the biology underlying cell-fate restrictions and might offer a new avenue for studying neurological diseases.