An improved method for the synthesis of gamma-DDB

Chuanjun Song; Peng Zhao; Zhiqiang Hu; Shuai Shi; Yanmei Cui; Junbiao Chang

doi:10.1016/j.bmcl.2010.01.166

An improved method for the synthesis of gamma-DDB

Bioorg Med Chem Lett. 2010 Apr 1;20(7):2297-8. doi: 10.1016/j.bmcl.2010.01.166. Epub 2010 Feb 6.

Authors

Chuanjun Song¹, Peng Zhao, Zhiqiang Hu, Shuai Shi, Yanmei Cui, Junbiao Chang

Affiliation

¹ Department of Chemistry, Zhengzhou University, Zhengzhou 450001, PR China. chjsong@zzu.edu.cn

PMID: 20207147
DOI: 10.1016/j.bmcl.2010.01.166

Abstract

A mild and efficient method for the synthesis gamma-DDB has been developed through anhydride-linker assisted intramolecular Ullmann reaction. Highly regioselective bromination of differentially protected gallate was realized by virtue of the introduction of NBS.

Publication types

Research Support, Non-U.S. Gov't

MeSH terms

Benzodioxoles / chemical synthesis*
Benzodioxoles / chemistry
Combinatorial Chemistry Techniques / economics
Combinatorial Chemistry Techniques / methods*
Halogenation
Molecular Structure
Stereoisomerism

Substances

Benzodioxoles